H-E-B Pharmacy hours are not necessarily the same as the operating hours of the H-E-B grocery store where the pharmacy is located. Current official H-E-B location pages show a common pharmacy schedule at many locations, but exceptions exist, making it important to check the specific pharmacy you plan to visit.
Many H-E-B pharmacies currently list longer hours Monday through Friday and reduced hours on Saturday and Sunday. Some locations have substantially different schedules, including pharmacies that are closed on Sunday.
Quick Answer
At many H-E-B locations currently checked, pharmacy hours are 8:00 AM to 8:00 PM Monday through Friday, 9:00 AM to 6:00 PM Saturday, and 10:00 AM to 5:00 PM Sunday.
However, these are not universal H-E-B Pharmacy hours. For example, H-E-B’s New Braunfels and Houston location in San Antonio lists different weekday and Saturday hours and is closed on Sunday. Always confirm your selected pharmacy before visiting.
H-E-B Pharmacy Hours at a Glance
| Day | Common Hours at Many Checked Locations | Location Variation |
|---|---|---|
| Monday | 8:00 AM–8:00 PM | Some locations differ |
| Tuesday | 8:00 AM–8:00 PM | Some locations differ |
| Wednesday | 8:00 AM–8:00 PM | Some locations differ |
| Thursday | 8:00 AM–8:00 PM | Some locations differ |
| Friday | 8:00 AM–8:00 PM | Some locations differ |
| Saturday | 9:00 AM–6:00 PM | Reduced hours at some locations |
| Sunday | 10:00 AM–5:00 PM | Some pharmacies may be closed |
This schedule reflects multiple official H-E-B location pages checked in October 2026 rather than a guarantee for every H-E-B Pharmacy.
What Time Does H-E-B Pharmacy Open?

Many of the H-E-B pharmacies checked currently open at 8:00 AM Monday through Friday.
Weekend opening times are commonly later:
- Saturday: 9:00 AM at many checked pharmacies
- Sunday: 10:00 AM at many checked pharmacies
There are exceptions. The New Braunfels and Houston H-E-B Pharmacy in San Antonio currently lists a 9:30 AM weekday opening time, demonstrating why the individual location schedule matters.
The grocery store itself may open earlier than its pharmacy. Seeing that an H-E-B store is open does not necessarily mean its pharmacy counter is open.
What Time Does H-E-B Pharmacy Close?
At many currently checked H-E-B locations, the pharmacy closes at 8:00 PM Monday through Friday.
Weekend closing times are generally earlier at those locations:
| Period | Common Closing Time at Checked Locations |
|---|---|
| Monday–Friday | 8:00 PM |
| Saturday | 6:00 PM |
| Sunday | 5:00 PM |
Again, exceptions exist. A pharmacy may close earlier or may not operate on Sunday at all.
H-E-B Pharmacy Hours by Day
Official location pages for several H-E-B stores currently show the following recurring schedule.
Monday Through Friday
Many checked pharmacies operate from 8:00 AM to 8:00 PM on weekdays.
This schedule is currently displayed at locations including 211 and Potranco, 281 and 1604, Foster Road, W. W. White, Loop 1604 and Blanco Road, and other H-E-B stores checked in San Antonio.
Saturday
A common Saturday schedule among the checked pharmacies is 9:00 AM to 6:00 PM.
Some locations close earlier. The New Braunfels and Houston H-E-B Pharmacy, for example, currently lists Saturday hours of 9:00 AM to 3:00 PM.
Sunday
Many checked H-E-B pharmacies list Sunday hours of 10:00 AM to 5:00 PM.
Sunday service should not be assumed at every store. The New Braunfels and Houston H-E-B Pharmacy currently lists no Sunday pharmacy hours and specifically indicates that its pharmacy is closed Sunday.
Do H-E-B Pharmacy Hours Vary by Location?
Yes. Current H-E-B location information confirms that pharmacy schedules can vary.
For example, several San Antonio pharmacies checked in October 2026 list:
Monday–Friday: 8:00 AM–8:00 PM
Saturday: 9:00 AM–6:00 PM
Sunday: 10:00 AM–5:00 PM
However, the New Braunfels and Houston location lists:
Monday–Friday: 9:30 AM–6:30 PM
Saturday: 9:00 AM–3:00 PM
Sunday: Closed
That is a meaningful difference, particularly if you need to pick up a prescription in the evening or on Sunday.
Sample H-E-B Pharmacy Location Comparison
The following comparison uses current official H-E-B location information checked in October 2026.
| H-E-B Location | Monday–Friday | Saturday | Sunday |
|---|---|---|---|
| 211 and Potranco, San Antonio | 8 AM–8 PM | 9 AM–6 PM | 10 AM–5 PM |
| 281 and 1604, San Antonio | 8 AM–8 PM | 9 AM–6 PM | 10 AM–5 PM |
| Foster Road, San Antonio | 8 AM–8 PM | 9 AM–6 PM | 10 AM–5 PM |
| W. W. White, San Antonio | 8 AM–8 PM | 9 AM–6 PM | 10 AM–5 PM |
| Loop 1604 and Blanco Road, San Antonio | 8 AM–8 PM | 9 AM–6 PM | 10 AM–5 PM |
| New Braunfels and Houston, San Antonio | 9:30 AM–6:30 PM | 9 AM–3 PM | Closed |
These examples demonstrate location differences and should not be interpreted as a nationwide schedule for every H-E-B Pharmacy.
H-E-B Pharmacy Sunday Hours
A frequently displayed Sunday schedule among the H-E-B pharmacies checked is 10:00 AM to 5:00 PM.
However, Sunday is particularly important to verify before making a trip because not every pharmacy follows that schedule. At least one current official H-E-B location page checked for this guide shows its pharmacy as closed Sunday.
The grocery portion of the same store can remain open even when the pharmacy is closed.
H-E-B Pharmacy Saturday Hours
Many checked H-E-B pharmacies list 9:00 AM to 6:00 PM on Saturday.
Reduced Saturday schedules exist. A pharmacy that normally stays open until the evening during the workweek may close several hours earlier on Saturday.
Check the pharmacy schedule specifically rather than relying on the main H-E-B store hours.
H-E-B Pharmacy Holiday Hours
H-E-B publishes special operating information for major holidays, and pharmacy schedules can differ substantially from regular hours.
Current official H-E-B holiday information lists the following pharmacy arrangements for several major holidays:
| Holiday | H-E-B Pharmacy Status/Hours |
|---|---|
| Memorial Day | 10:00 AM–5:00 PM |
| Independence Day | 10:00 AM–5:00 PM |
| Labor Day | 10:00 AM–5:00 PM |
| Thanksgiving Day | Closed |
| Christmas Eve | Closes at 5:00 PM |
| Christmas Day | Closed |
| New Year’s Day | 10:00 AM–5:00 PM |
Holiday schedules deserve a separate check because regular weekday or weekend pharmacy hours may not apply.
Is H-E-B Pharmacy Open on Thanksgiving?
H-E-B’s current holiday information lists its pharmacies as closed on Thanksgiving Day.
The grocery store may operate for limited hours on Thanksgiving even though the pharmacy is closed. Store operating hours therefore should not be used to determine pharmacy availability.
Is H-E-B Pharmacy Open on Christmas Eve?
H-E-B’s published holiday schedule states that pharmacies close at 5:00 PM on Christmas Eve.
That is earlier than the regular closing time at many pharmacies, so customers needing prescriptions before Christmas should account for the reduced schedule.
Is H-E-B Pharmacy Open on Christmas Day?
H-E-B lists its pharmacies as closed on Christmas Day.
H-E-B stores, curbside service, and home delivery are also listed as closed for Christmas Day in the current holiday information.
Is H-E-B Pharmacy Open on New Year’s Day?
H-E-B’s current holiday information lists pharmacy hours of 10:00 AM to 5:00 PM on New Year’s Day.
Is H-E-B Pharmacy Open on Memorial Day?
The published H-E-B holiday schedule lists pharmacy hours of 10:00 AM to 5:00 PM on Memorial Day.
Is H-E-B Pharmacy Open on July 4th?
H-E-B currently lists pharmacy hours of 10:00 AM to 5:00 PM on Independence Day.
Is H-E-B Pharmacy Open on Labor Day?
H-E-B’s holiday information lists pharmacies as operating from 10:00 AM to 5:00 PM on Labor Day.
Because holiday schedules can be updated, confirming the current holiday information for your selected location remains worthwhile.
H-E-B Store Hours vs. Pharmacy Hours
One of the easiest mistakes to make is confusing regular H-E-B store hours with H-E-B Pharmacy hours.
They are separate schedules.
For example, several H-E-B stores checked for this guide list grocery store hours of 6:00 AM to 11:00 PM every day, while their pharmacies operate:
- 8:00 AM–8:00 PM Monday through Friday
- 9:00 AM–6:00 PM Saturday
- 10:00 AM–5:00 PM Sunday
Someone arriving at 7:00 AM could therefore find the grocery store open but the pharmacy still closed. The same issue can occur later in the evening after the pharmacy has closed.
Always look for the section specifically labeled Pharmacy hours when checking an H-E-B location.
H-E-B Pharmacy Services
Services differ between locations, so availability should be checked at the pharmacy you intend to use.
Official H-E-B location pages currently identify pharmacy services at various stores such as:
- Prescription services
- Prescription delivery at participating locations
- Immunizations at participating pharmacies
- Compounding at selected locations
- Drive-thru pharmacy service at selected locations
- ScripTalk at selected locations
Not every H-E-B Pharmacy provides every listed service. For example, current official location pages show drive-thru pharmacy service at numerous stores, but it should not be assumed for every location.
Does H-E-B Pharmacy Have a Drive-Thru?
Some H-E-B Pharmacy locations have a drive-thru, but availability is location-specific.
Official H-E-B pages for several locations checked for this guide identify Drive Thru among their pharmacy services. Other stores may have different facilities.
A drive-thru listing also does not establish that its hours differ from or exactly match the pharmacy counter schedule. Check the selected store’s current information if drive-thru service is important to your visit.
How to Check H-E-B Pharmacy Hours Near You
The most reliable approach is to check the specific H-E-B location rather than depending solely on general chain-wide hours.
Use this order:
- Search for your H-E-B store using H-E-B’s official store finder.
- Open the individual store information.
- Find the separate Pharmacy hours section.
- Check the day you plan to visit.
- Review special holiday information when visiting around a major holiday.
- Call the pharmacy directly if you need confirmation before an important prescription pickup.
Google Maps can provide a useful secondary check, but general store hours should not be treated as proof of pharmacy hours.
Why Your Local H-E-B May Be Open When the Pharmacy Is Closed
An H-E-B supermarket and the pharmacy inside it operate on different schedules.
The store may open earlier, remain open later, or operate during a holiday period when the pharmacy is closed. This is especially relevant:
- Early in the morning
- Later in the evening
- On Saturdays
- On Sundays
- On Thanksgiving
- On Christmas
- During reduced holiday schedules
Check the pharmacy-specific listing whenever your visit depends on speaking with pharmacy staff or accessing a service that requires the pharmacy to be open.
Read Next
Explore more helpful guides from this category.
Frequently Asked Questions
What Are the Regular H-E-B Pharmacy Hours?
Many H-E-B pharmacies checked currently list 8:00 AM to 8:00 PM Monday through Friday, 9:00 AM to 6:00 PM Saturday, and 10:00 AM to 5:00 PM Sunday. Individual locations can follow different schedules.
What Time Does H-E-B Pharmacy Open?
Many checked H-E-B pharmacies open at 8:00 AM on weekdays, 9:00 AM Saturday, and 10:00 AM Sunday. These times are not universal, so check your selected pharmacy.
What Time Does H-E-B Pharmacy Close?
A common schedule among the locations checked has the pharmacy closing at 8:00 PM on weekdays, 6:00 PM Saturday, and 5:00 PM Sunday. Some pharmacies close earlier.
Is H-E-B Pharmacy Open on Sunday?
Many H-E-B pharmacies are open Sunday, commonly from 10:00 AM to 5:00 PM among the locations checked. However, some locations are closed Sunday.
Is H-E-B Pharmacy Open on Saturday?
Yes, many H-E-B pharmacies operate on Saturday. 9:00 AM to 6:00 PM is a common schedule among the official location pages checked, although some stores have shorter Saturday hours.
Is H-E-B Pharmacy Open on Thanksgiving?
H-E-B’s current official holiday information lists pharmacies as closed on Thanksgiving Day.
Is H-E-B Pharmacy Open on Christmas Day?
No. H-E-B’s published holiday information lists pharmacies as closed on Christmas Day.
Are H-E-B Store and Pharmacy Hours the Same?
No. H-E-B grocery stores can open earlier and close later than their pharmacies. Always check the pharmacy-specific hours rather than using the supermarket’s operating schedule.
Sources & Verification
This guide was checked in October 2026 against current H-E-B official location information and H-E-B’s published holiday-hours information. Multiple H-E-B Pharmacy location schedules were compared to determine whether the commonly displayed hours were consistent and to identify meaningful exceptions.
The research confirms that many checked pharmacies share the same weekday and weekend schedule, but it also confirms that H-E-B Pharmacy hours are not universal across all locations. Holiday hours can differ from regular pharmacy schedules as well. Pasted text
Before You Go
For many H-E-B pharmacies, a useful reference schedule is 8 AM–8 PM Monday through Friday, 9 AM–6 PM Saturday, and 10 AM–5 PM Sunday. However, individual H-E-B pharmacies can open later, close earlier, or remain closed on Sunday.
Before heading out—especially for an evening, weekend, or holiday visit—check the pharmacy-specific hours for your selected H-E-B location, not just the grocery store’s opening and closing times.





